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We all know when you eliminate sugar and carbs, the weight falls off. How can this be when fat has more than twice as many calories per gram as carbs? A gram of fat has about nine calories, while a gram of carbohydrate has about four calories. You could eat twice as many carbohydrates as fat for the same amount of calories, yet the minute you increase healthy fat and protein (low in carbs), you lose weight and feel better. Carbs don't sustain or satiate you like healthy fat and protein, so you end up consuming 4-6x's the carbs that |
Abstract
BACKGROUND/AIMS:
The present study was conducted to examine the antidiabetic effects of xylitol in a type 2 diabetes rat model.
METHODS:
Six-week-old male Sprague-Dawley rats were randomly divided into 3 groups: normal control (NC), diabetic control (DBC) and xylitol (XYL). Diabetes was induced only in the DBC and XYL animal groups by feeding them a 10% fructose solution for 2 weeks followed by an injection (i.p.) of streptozotocin (40 mg/kg body weight). One week after the streptozotocin injection, the animals with a nonfasting blood glucose level of >300 mg/dl were considered to be diabetic. The XYL group was fed further with a 10% xylitol solution, whereas the NC and DBC groups were supplied with normal drinking water.
RESULTS:
After 5 weeks of intervention, food and fluid intake, body weight, blood glucose, serum fructosamine and most of the serum lipids were significantly decreased, and serum insulin concentration and glucose tolerance ability was significantly increased in the XYL group compared to the DBC group. Liver weight, liver glycogen and serum triglycerides were not influenced by feeding with xylitol.
CONCLUSION:
The data of this study suggest that xylitol can be used not only as a sugar substitute but also as a supplement to antidiabetic food and other food products.
Copyright © 2012 S. Karger AG, Basel.
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